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Note: TUPE regulations can be very complex and we recommend that anyone affected by them should seek legal advice before taking action. Forum members should call our helpline on 0845 130 1722 to take advice and make sure you're covered by insurance. When do TUPE regulations apply? The Regulations apply: When all or part of a business or partnership is sold or transferred Where a company, or part of it, is acquired by another company (that is, if the acquiring company buys or acquires the assets and runs the business rather than acquiring shares only) Where two companies combine to